Natalia CORREIA TEIXERA

Maître de Conférences Université de Lille, IUT

Bâtiment P5 - 225
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0) 3 20 33 59 02
Fax: +33 (0)3 20 43 40 84
Courriel : Envoyer un mel à Natalia CORREIA TEIXERA
Identifiant ORCID : 0000-0002-3714-3190

Equipe: Matériaux moléculaires et thérapeutiques

Recherche

Mobilité moléculaire et transformations de phase de matériaux moléculaires. Formes solides désordonnées - cristal désordonné métastable, cristal liquide, solide semi-cristallin ou amorphe. Investigation de l'état physique de nouveaux matériaux pour la formulation de molécules pharmaceutiques. Systèmes multi-composants : co-cristaux, co-amorphes, matériaux sous nanoconfinement. Spectroscopie de Relaxation Diélectrique (DRS). Courants de Dépolarisation Thermo-stimulés (TSDC).

Enseignement

IUT A – Département Mesures Physique (Mécanique vibratoire et acoustique ; Systèmes Optiques (photométrie et colorimétrie) ; Groupements fonctionnels)

Thèses en cours

• Fabien PUGA MONTESDEOCA, Etude numérique et expérimentale des intéractions intermoléculaires et du désordre dynamique dans les cocristaux d'intérêt pharmaceutique . Thèse débutée en 2023. Co-direction: Frédéric AFFOUARD.

Thèses soutenues

• Luisa ROCA PAIXAO, Investigation de l'état physique de nouveaux matériaux pour la formulation de molécules pharmaceutiques de très faible solubilité . Thèse soutenue en 2020. Co-direction: Frédéric AFFOUARD.
• Benjamin MALFAIT, Amélioration de la stabilité et de la biodisponibilité de matériaux pharmaceutiques et de biopharmaceutiques par confinement dans des systèmes à libération controlée . Thèse soutenue en 2019. Co-direction: Alain HEDOUX. Devenir post-thèse: Material Scientist | Solid-state expertise on small organic molecules.

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

21. M. Guerain, N. T. Correia, L.-V. Roca Paixao, H. Chevreau, F. Affouard, Using synchrotron high-resolution powder X-ray diffraction for the structure determination of a new cocrystal formed by two active principle ingredients, Acta Crystallographica Section C Structural Chemistry 80;2, 37-42 (2024), [doi: 10.1107/s2053229624000639, LillOA]
20. T. Cordeiro, I. Matos, F. Danede, J.C. Sotomayor, I.M. Fonseca, M.C. Corvo, M. Dionísio, M.T. Viciosa, F. Affouard, N. T. Correia, Evidence of Strong Guest–Host Interactions in Simvastatin Loaded in Mesoporous Silica MCM-41, Pharmaceutics 15;5, 1320 (2023), [doi: 10.3390/pharmaceutics15051320, LillOA]
19. L.-V. Roca Paixao, N. T. Correia, F. Danede, M. Guerain, F. Affouard, Carbamazepine/Tartaric Acid Cocrystalline Forms: When Stoichiometry and Synthesis Method Matter, Crystal Growth & Design 23;3, 1355-1369 (2023), [doi: 10.1021/acs.cgd.2c00859, LillOA]
18. L.-V. Roca Paixao, N. T. Correia, F. Danede, M.T. Viciosa, A.L. Morritt, Y.Z. Khimyak, F. Affouard, Nature of the Structural and Dynamical Disorder in Organic Cocrystals with a True Nanometric Size Channel-Like Architecture, Crystal Growth & Design 23;1, 120-133 (2023), [doi: 10.1021/acs.cgd.2c00815, LillOA]
17. P. d’Orey, T. Cordeiro, M.A.O. Lourenço, I. Matos, F. Danede, J.C. Sotomayor, I.M. Fonseca, P. Ferreira, N. T. Correia, M. Dionísio, How Molecular Mobility, Physical State, and Drug Distribution Influence the Naproxen Release Profile from Different Mesoporous Silica Matrices, Molecular Pharmaceutics 18;3, 898-914 (2021), [doi: 10.1021/acs.molpharmaceut.0c00908, LillOA]
16. A.C. Santos, S.P. Alves, G. Carvalhão, N. T. Correia, M.T. Viciosa, J.P.S. Farinha, Phase diagrams of temperature-responsive copolymers p(MEO2MA-co-OEGMA) in water, Polymer 228, 123858 (2021), [doi: 10.1016/j.polymer.2021.123858, LillOA]
15. Y. Vaksler, D. Benedis, A. Dyshin, R. Oparin, N. T. Correia, F. Capet, S. Shishkina, M. Kiselev, A. Idrissi, Spectroscopic characterization of single co-crystal of mefenamic acid and nicotinamide using supercritical CO2, Journal of Molecular Liquids 334, 116117 (2021), [doi: 10.1016/j.molliq.2021.116117, LillOA]
14. B. Malfait, L. Paccou, N. T. Correia, Y. Guinet, A. Hedoux, Identification of an amorphous-amorphous two-step transformation in indomethacin embedded within mesoporous silica, Microporous and Mesoporous Materials 328, 111502 (2021), [doi: 10.1016/j.micromeso.2021.111502, LillOA]
13. B. Atawa, N. Couvrat, F. Affouard, N. T. Correia, G. Coquerel, A. Saiter-Fourcin, Impact of chirality on the amorphous state of conglomerate forming systems: a case study of N-acetyl-α-methylbenzylamine, Physical Chemistry Chemical Physics 23;42, 24282-24293 (2021), [doi: 10.1039/d1cp03843e, LillOA]
12. M. Guerain, Y. Guinet, N. T. Correia, L. Paccou, F. Danede, A. Hedoux, Polymorphism and stability of ibuprofen/nicotinamide cocrystal: The effect of the crystalline synthesis method, International Journal of Pharmaceutics 584, 119454 (2020), [doi: 10.1016/j.ijpharm.2020.119454, LillOA]
11. S. Inocencio, T. Cordeiro, I. Matos, F. Danede, J.C. Sotomayor, I.M. Fonseca, N. T. Correia, M.C. Corvo, M. Dionísio, Ibuprofen incorporated into unmodified and modified mesoporous silica: From matrix synthesis to drug release, Microporous and Mesoporous Materials 310, 110541 (15 p.) (2020), [doi: 10.1016/j.micromeso.2020.110541, LillOA]
10. B. Malfait, N. T. Correia, C. Ciotonea, J. Dhainaut, J.-P. Dacquin, s. royer, N. Tabary, Y. Guinet, A. Hedoux, Manipulating the physical states of confined ibuprofen in SBA-15 based drug delivery systems obtained by solid-state loading: Impact of the loading degree, The Journal of Chemical Physics 153;15, 154506 (2020), [doi: 10.1063/5.0020992, LillOA]
9. M. Guerain, P. Derollez, L.-V. Roca Paixao, C. Dejoie, N. T. Correia, F. Affouard, Structure determination of Carbamazepine/DL-TA co-crystal by synchrotron powder X-ray diffraction, Acta Crystallographica Section C Structural Chemistry 76, (2020), [LillOA]
8. J. Knapik-Kowalczuk, K. Chmiel, K. Jurkiewicz, N. T. Correia, W. Sawicki, M. Paluch, Physical Stability and Viscoelastic Properties of Co-Amorphous Ezetimibe/Simvastatin System, Pharmaceuticals 12;1, 40 (2019), [doi: 10.3390/ph12010040, LillOA]
7. T. Starciuc, B. Malfait, F. Danede, L. Paccou, Y. Guinet, N. T. Correia, A. Hedoux, Trehalose or sucrose; which of the two should be used for stabilizing proteins in the solid state? A dilemma investigated by in-situ micro-Raman and dielectric relaxation spectroscopies during and after freeze-drying, Journal of Pharmaceutical Sciences 109;1, 496-504 (2019), [doi: 10.1016/j.xphs.2019.10.055, LillOA]
6. L.-V. Roca Paixao, N. T. Correia, F. Affouard, Affinity prediction computations and mechanosynthesis of carbamazepine based cocrystals, Crystengcomm 21;45, 6991-7001 (2019), [doi: 10.1039/c9ce01160a, LillOA]
5. B. Atawa, N. T. Correia, N. Couvrat, F. Affouard, G. Coquerel, E. Dargent, A. Saiter, Molecular Mobility of Amorphous N-Acetyl-α-Methylbenzylamine and Debye Relaxation evidenced by Dielectric Relaxation Spectroscopy and Molecular Dynamic Simulations, Physical Chemistry Chemical Physics 21, 702 - 717 (2019), [doi: 10.1039/C8CP04880K, LillOA]
4. M.T. Ottou Abe, M.T. Viciosa, N. T. Correia, F. Affouard, Impact of chirality on peculiar ibuprofen molecular dynamics: hydrogen bonding organization and syn vs. anti carboxylic group conformations, Physical Chemistry Chemical Physics 20, 29528-29538 (2018), [doi: 10.1039/C8CP04837A, LillOA]
3. A. Benazzouz, E. Dudognon, N. T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2017), [doi: 10.1007/s10570-016-1148-y, LillOA]
2. E. Dudognon, N. T. Correia, F. Danede, M. Descamps, Solid-Solid Transformation in Racemic Ibuprofen, Pharmaceutical Research 30, 81-89 (2013), [doi: 10.1007/s11095-012-0851-0, LillOA]
1. A. Hedoux, Y. Guinet, P. Derollez, E. Dudognon, N. T. Correia, Raman spectroscopy of racemic ibuprofen: Evidence of molecular disorder in phase II, International Journal of Pharmaceutics 421, 45-52 (2011), [doi: 10.1016/j.ijpharm.2011.09.015, LillOA]

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Communications

10. L.-V. Roca Paixao, N. T. Correia, F. Danede, M.T. Viciosa, A. Morritt, Y.Z. Khimyak, F. Affouard, Nature of the disorder in organic cocrystals of pharmaceutical interest with a channel-like architecture, Conférence invitée, 9th International Discussion Meeting on Relaxations in Complex Systems (9 IDMRCS), Chiba, Japon, Aou 2023 [LillOA]
9. Y.Z. Khimyak, L. Fabian, A. Morritt, M. Nowak, N. T. Correia, F. Affouard, M. T. Ruggiero, K.P. Nartowski, Understanding phase transitions and nature of disorder in pharmaceutical materials: polymorphs, co-crystals and nano-confined systems, Communication dans un congrès sans actes, Taming Disorder in Solid Materials, Durham, Royaume-Uni, Déc 2023 [LillOA]
8. N. T. Correia, F. Affouard, SYSTÈMES PHARMACEUTIQUES PAR BDS & MD : QUELQUES CAS CURIEUX, Communication dans un congrès sans actes, GDR REEPOS 2023 & SDM 3, Toulouse, France, Juin 2023 [LillOA]
7. T. Cordeiro, M.T. Viciosa, M. Dionísio, F. Affouard, N. T. Correia, Amorphous Simvastatin Confined in MCM-41: Where have the β-JG and α-relaxation processes gone?, Communication dans un congrès sans actes, 9th International Discussion Meeting on Relaxations in Complex Systems (9IDMRCS), Chiba City, Japon, Aou 2023 [LillOA]
6. N. T. Correia, Interests of dielectric relaxation spectroscopy to investigate different properties of pharmaceuticals, Conférence invitée, International Conference on Science and Technology of Pharmaceutical Glass, Tsukuba, Japon, Aou 2023 [LillOA]
5. L.-V. Roca Paixao, F. Danede, N. T. Correia, F. Affouard, WHEN RESIDUAL WATER INFLUENCES THE COCRYSTALLIZATION OUTPUT: THE CARBAMAZEPINE AND TARTARIC ACID CASE, Communication dans un congrès sans actes, Journées SolvATE 2021, Lille, France, Déc 2021 [LillOA]
4. N. T. Correia, T. Cordeiro, F. Affouard, I. Matos, F. Danede, J. Sotomayor, M. Corvo, I. Fonseca, M. Dionísio, M.T. Viciosa, Simvastatine confinée dans MCM-41 : désordre dynamique, organisations/interactions moléculaires et leurs implications sur la vitesse de dissolution et le profil de libération, Poster, Conference Internationale "Matériaux 2022", Lille, France, Oct 2022 [LillOA]
3. N. T. Correia, L.-V. Roca Paixao, F. Affouard, Carbamazepine/Tartaric Acid Ordered and Disordered Cocrystalline Forms: When Stoichiometry and Synthesis Method Matter, Communication dans un congrès sans actes, CGOM14: 14 th International Conference on Crystal Growth of Organic Materials, Bruxelles, Belgique, Sep 2022 [LillOA]
2. N. T. Correia, L.-V. Roca Paixao, F. Danede, M.T. Viciosa, A.L. Morritt, Y.Z. Khimyak, F. Affouard, Dynamic Disorder in a Nano-Sized Channel-Shaped Pharmaceutical Cocrystal Architecture, Conférence invitée, 11th Conference on Broadband Dielectric Spectroscopy and its applications, San Sebastian, Espagne, Sep 2022 [LillOA]
1. L.-V. Roca Paixao, M.T. Viciosa, N. T. Correia, F. Affouard, Dynamical disorder in the solid state: Insights from dielectric relaxation spectroscopies, Poster, 32nd European Crystallographic Meeting (ECM32), Vienna, Autriche, Aou 2019 [LillOA]

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