UMET - Liste des communicatons de Alain HEDOUX

Presentations with publication

  1. S. Nasser, A. Giuliani, I. Dewaele, A. Hedoux, G. Delaplace, Evolution of secondary structure of milk powder during storage : Multivariate analysis FTIR and Circular Dichroism, International, Conference on Food Chemistry and Hydrocolloids, Canada, Sep 2016 [LillOA]

Research seminars

  1. A. Hedoux, Original features induced by milling analyzed by raman spectroscopy, AstraZeneca, Göteborg, Suède, Oct 2018 [LillOA]
  2. A. Hedoux, Mechanisms of protein denaturation and stabilization from raman investigations, Astrazeneca, Göteborg, Suède, Oct 2018 [LillOA]
  3. A. Hedoux, Insights into bioprotection mechanisms by disaccharides, AstraZeneca, Göteborg, Suède, Oct 2018 [LillOA]
  4. A. Hedoux, The contribution of the low-frequency raman spectroscopy (lfrs) to the structural description of disordered molecular systems and their transformations: application to pharmaceuticals, Astrazeneca, Göteborg, Suède, Oct 2018 [LillOA]

Invited presentations

  1. T. Starciuc, L. Paccou, Y. Guinet, A. Hedoux, Mechanism of protein stabilization analyzed from in-situ Raman investigations during freeze-drying procedures, Freeze-drying of pharmaceuticals & biologicals, Garmisch-Partenkirchen, Allemagne, Sep 2018 [LillOA]
  2. T. Starciuc, A. Hedoux, Y. Guinet, L. Paccou, Mechanisms of protein denaturation and stabilization analyzed in-situ during the freeze-drying process by micro-Raman spectroscopy, 8th International Discussion Meeting on Relaxations in Complex Systems (8IDMRCS), Wisla, Pologne, Jul 2017 [LillOA]
  3. T. Starciuc, L. Paccou, Y. Guinet, A. Hedoux, Protein denaturation and stabilization during freeze-drying analyzed from in-situ micro Raman investigations, International Symposium On the Properties of Water, ISOPOW XIII, Lausanne, Suisse, Jun 2016 [LillOA]
  4. A. Hedoux, L. Paccou, Y. Guinet, The contribution of the low-frequency Raman spectroscopy to the structural description of disordered molecular systems and their transformations: application to pharmaceuticals, SciX 2015, Providence (Rhode Island), Etats-Unis d'Amérique, Oct 2015 [LillOA]
  5. A. Hedoux, L. Paccou, Y. Guinet, Solid state transformations of APIs induced by various stresses analyzed in real time by Raman spectroscopy, AMPTEC, Lille, France, Jul 2014 [LillOA]
  6. A. Hedoux, L. Paccou, Y. Guinet, Phase transformation of APIs, Analyzed by Raman spectroscopy, IDEA Closing conference, Lille, France, Jun 2013 [LillOA]
  7. A. Hedoux, L. Paccou, Y. Guinet, Solid state transformations of APIs induced by manufacturing processes analyzed by micro-Raman spectroscopy, 7th PSSRC Symposium 'Openday', Lille, France, Jul 2013 [LillOA]
  8. A. Hedoux, L. Paccou, Y. Guinet, New Insights on bioprotective mechanisms, 7th International Discussion Meeting on Relaxations in Complex Systems, Barcelone, France, Jul 2013 [LillOA]
  9. A. Lerbret, A. Hedoux, Y. Guinet, F. Affouard, Lyophilized proteins: influence of residual water on stability, European/Japanese Molecular Liquids Group) annual meeting 2013, Villeneuve d'Ascq, France, Sep 2013 [LillOA]
  10. A. Hedoux, Phase transformations of APIs under various stresses analyzed by Raman spectroscopy, 14th International Workshop on Physical Characterization of Pharmaceutical Solids, Barcelone, Espagne, Jun 2012 [LillOA]
  11. S. Hubert, S. Briancon, A. Hedoux, Y. Guinet, D.D. Ligny, B. Champagnon, F. Puel, Micro-Raman spectroscopy of caffeine polymorphs in tablets: comparison between low and high frequency investigations, 14th International Workshop on Physical Characterization of Pharmaceutical Solids, Barcelone, Espagne, Jun 2012 [LillOA]
  12. A. Hedoux, Raman study of molecular motions in organic glass formers : Application to pharmaceuticals, 2nd IWGFS, Pusan, Corée du Sud, Nov 2010 [LillOA]

Oral presentations

  1. M. Guerain, P. Derollez, C. Dejoie, N. T. Correia, F. Danede, F. Affouard, L. Paccou, Y. Guinet, A. Hedoux, C. Dejoie, Analyse structurale de matériaux moléculaires thérapeutiques cocristallisés par diffraction des rayons X, Rayons X et Matière 2019, Nancy, France, Nov 2019 [LillOA]
  2. M. Latreche, J.-F. Willart, A. Hedoux, Efficient solid state transformation protocol to determine the solubility of drugs into polymers, The 1st International Conference on Contemporary Pharmacy Challenges, Wisla, Pologne, Sep 2018 [LillOA]
  3. B. Malfait, N. T. Correia, A. Mussi, L. Paccou, Y. Guinet, A. Hedoux, Solid-state loading of pharmaceutical materials within mesoporous silica matrices, 1st International Conference on Contemporary Pharmacy Challenges: 1st International Conference on Contemporary Pharmacy Challenges:, Wisla, Pologne, Sep 2018 [LillOA]
  4. J. Junthip, N. Tabary, B. Martel, N. Blanchemain, F. Chai, M. Maton, C. Neut, A. Hedoux, D. Landy, Multilayer assembly of oppositely charged cyclodextrin polymers on textile for controlled drug delivery, Pure and Applied Chemistry International Conference (PACCON), Bangkok, Thaïlande, Feb 2016 [LillOA]
  5. J. Junthip, N. Tabary, B. Martel, N. Blanchemain, F. Chai, A. Hedoux, D. Landy, L. Leclercq, Dual cyclodextrin polyelectrolyte multilayer coatings on textile for controlled drug delivery, EuroCD2015, Lille, France, Oct 2015 [LillOA]
  6. A. Lerbret, F. Affouard, A. Hedoux, M. Descamps, Protein-matrix interactions in trehalose/glycerol mixtures at low water contents, International Symposium On the Properties of Water, ISOPOW XIII, Lausanne, Suisse, Jun 2016 [LillOA]
  7. G. Bellavia, L. Paccou, Y. Guinet, A. Hedoux, The solvent dynamical transition is a necessary precursor to promote the protein unfolding, International Symposium On the Properties of Water, ISOPOW XIII, Lausanne, Suisse, Jun 2016 [LillOA]
  8. G. Bellavia, L. Paccou, Y. Guinet, A. Hedoux, Role of glycerol on trehalose to enhance biostability in relation with fast anharmonic and quasi-harmonic motions, ProtStab2014 : 10th International Conference on Protein Stabilisation, Stresa, Italie, May 2014 [LillOA]
  9. T. Starciuc, L. Paccou, Y. Guinet, A. Hedoux, Micro-Raman Spectroscopy used as a PAT tool and for real time monitoring of protein stability during freeze drying, SciX 2015, Providence (Rhode Island), Etats-Unis d'Amérique, Sep 2015 [LillOA]
  10. G. Bellavia, A. Hedoux, L. Paccou, S. Achir, Y. Guinet, J. Siepmann, Raman Scattering As a Tool to Investigate Protein Hydration Shell, Water at Interfaces: new developments in physics, chemistry and biology, Ecole des Physique des Houches, Les Houches, France, Apr 2013 [LillOA]
  11. G. Bellavia, A. Hedoux, L. Paccou, S. Achir, Y. Guinet, Analysis of bulk and hydration water during thermal lysozyme denaturation, Frontiers in Water Biophysics, Perugia, Italie, Sep 2012 [LillOA]
  12. S. Hubert, S. Briancon, A. Hedoux, Y. Guinet, L. Paccou, H. Fessi, F. Puel, Analysis of Caffeine using DSC and low Frequency Micro-Raman Spectroscopy, 12th International Conference on Pharmacy and Applied Physical Chemistry, Graz, Australie, May 2012 [LillOA]
  13. A. Lerbret, F. Affouard, A. Hedoux, S. Krenzlin, J. Siepmann, M.-C. Bellissent-Funel, M. Descamps, How strongly does trehalose interact with lysozyme at low water contents? Insights from molecular dynamics simulation and inelastic neutron scattering, Frontiers in Water Biophysics, Perugia, Italie, Sep 2012 [LillOA]
  14. B. Malfait, N. T. Correia, A. Mussi, L. Paccou, Y. Guinet, A. Hedoux, Solid-state loading of pharmaceutical materials within mesoporous silica matrices, 1st International Conference on Contemporary Pharmacy Challenges (1 ICCPC) Amorphous Pharmaceuticals and Biopharmaceuticals, Wisla, Pologne, Sep 2018 [LillOA]
  15. S. Hubert, S. Briancon, A. Hedoux, Y. Guinet, L. Paccou, H. Fessi, F. Puel, Process induced Transformations during Tablet Manufacturing: Phase Transition Analysis of Caffeine from Low Frequency Raman mapping, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turquie, Mar 2012 [LillOA]
  16. G. Bellavia, L. Paccou, Y. Guinet, J. Siepmann, A. Hedoux, Protein stability enhancing by a small amount of glycerol in trehalose solution: a Raman study, Advanced School on Chemistry, Sao Paulo, Brésil, Aug 2011 [LillOA]
  17. A. Lerbret, F. Affouard, P. Bordat, A. Hedoux, Y. Guinet, M. Descamps, Molecular dynamics simulation and Raman scattering study of lysozyme in disaccharide aqueous solutions, Frontiers in Water Biophysics 2010, Trieste, Italie, May 2010 [LillOA]

Poster presentations

  1. M. Gehrke, T. Rongthong, G. Tourrel, D. Gnansia, P. Oliveira, J.-F. Willart, L. Paccou, Y. Guinet, A. Hedoux, C. Vincent, F. Siepmann, J. Siepmann, Homogeneity, drug release and swelling of dexamethasone loaded cochlear implants, 11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Granada, Espagne, Mar 2018 [LillOA]
  2. B. Malfait, N. T. Correia, A. Mussi, Y. Guinet, A. Hedoux, Confinement of APIs inside porous silicate matrices by milling: analysis of the physical state and stability of confined APIs, 11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Grenade, Espagne, Mar 2018 [LillOA]
  3. T. Starciuc, N. T. Correia, Y. Guinet, L. Paccou, A. Hedoux, Freeze drying of pharmaceuticals and biologicals, Freeze Drying of Pharmaceuticals and Biologicals, Garmisch-Partenkirchen, Allemagne, Sep 2018 [LillOA]
  4. S. Achir, G. Bellavia, F. Affouard, A. Hedoux, MD simulations and experimental studies of freeze-dried protein: protein stability in glassy matrices, 7 IDMRCS : 7th International Discussion Meeting on Relaxations in Complex Systems, Barcelone, Espagne, Jul 2013 [LillOA]
  5. A. Lerbret, F. Affouard, A. Hedoux, B. Annighöfer, M.-C. Bellissent-Funel, Neutron scattering study of lysozyme solution under high pressures, 5th European Conference on Neutron Scattering, Prague, République tchèque, Jul 2011 [LillOA]
  6. A. Lerbret, F. Affouard, P. Bordat, A. Hedoux, Y. Guinet, M. Descamps, Molecular dynamics simulation and Raman scattering study of lysozyme in disaccharide aqueous solutions, NDBB Meeting, Grenoble, France, Jan 2011 [LillOA]
  7. S. Krenzlin, A. Hedoux, Y. Guinet, L. Paccou, M.-P. Flament, F. Siepmann, J. Siepmann, Lysozyme loaded lipid implants: How trehalose effectively preserves protein activity, Innovation in drug delivery: From preformulation to development through innovative evaluation process-ADRITELF/APGI, Aix en Provence, France, Sep 2010 [LillOA]
  8. S. Krenzlin, A. Hedoux, L. Paccou, F. Siepmann, M.-P. Flament, J. Siepmann, Conformational stability of L-lactate dehydrogenase during freeze drying and storage, 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, La Valette, Malte, Mar 2010 [LillOA]
  9. S. Krenzlin, J. Dutet, A. Hedoux, Y. Guinet, L. Paccou, M.-P. Flament, F. Siepmann, J. Siepmann, Lysozyme loaded lipid implants: How trehalose effectively preserves protein activity, Innovation in drug delivery: From preformulation to development through innovative evaluation process-ADRITELF/APGI, Aix en Provence, France, Apr 2010 [LillOA]
  10. C. Velghe, Y. Karrout, S. Krenzlin, Y. Guinet, L. Paccou, M.-P. Flament, A. Hedoux, J. Siepmann, Impact of trehalose addition to lysozyme-loaded, lipid implants, 8th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Istanbul, Turquie, Mar 2012 [LillOA]