Natalia CORREIA TEIXERA

Maître de Conférences Université de Lille, IUT

Bâtiment P5 - 225
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0) 3 20 33 59 02
Fax: +33 (0)3 20 43 40 84
Courriel : Envoyer un mel à Natalia CORREIA TEIXERA
Identifiant ORCID : 0000-0002-3714-3190

Equipe: Matériaux moléculaires et thérapeutiques

Recherche

Mobilité moléculaire et transformations de phase de matériaux moléculaires. Formes solides désordonnées - cristal désordonné métastable, cristal liquide, solide semi-cristallin ou amorphe. Investigation de l'état physique de nouveaux matériaux pour la formulation de molécules pharmaceutiques. Systèmes multi-composants : co-cristaux, co-amorphes, matériaux sous nanoconfinement. Spectroscopie de Relaxation Diélectrique (DRS). Courants de Dépolarisation Thermo-stimulés (TSDC).

Enseignement

IUT A – Département Mesures Physique (Mécanique vibratoire et acoustique ; Systèmes Optiques (photométrie et colorimétrie) ; Groupements fonctionnels)

Thèses en cours

• Fabien PUGA MONTESDEOCA, Etude numérique et expérimentale des intéractions intermoléculaires et du désordre dynamique dans les cocristaux d'intérêt pharmaceutique . Thèse débutée en 2023. Co-direction: Frédéric AFFOUARD.

Thèses soutenues

• Luisa ROCA PAIXAO, Investigation de l'état physique de nouveaux matériaux pour la formulation de molécules pharmaceutiques de très faible solubilité . Thèse soutenue en 2020. Co-direction: Frédéric AFFOUARD.
• Benjamin MALFAIT, Amélioration de la stabilité et de la biodisponibilité de matériaux pharmaceutiques et de biopharmaceutiques par confinement dans des systèmes à libération controlée . Thèse soutenue en 2019. Co-direction: Alain HEDOUX. Devenir post-thèse: Material Scientist | Solid-state expertise on small organic molecules.

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

21. A. Shagurin, M.G. Kiselev, P. Jedlovszky, N. T. Correia, F. Affouard, N. Idrissi, Thermal Behavior and Local Structural Organization in Curcumin Polymorphs' Bulk Phase: A Molecular Dynamics Simulation Analysis., J Phys Chem B 129;33, (2025), [doi: 10.1021/acs.jpcb.5c04240, LillOA]
20. A. Shagurin, F.-A. Miannay, M.G. Kiselev, P. Jedlovszky, N. T. Correia, F. Affouard, N. Idrissi, Impact of Intermolecular Forces on Structural Changes and Local Density Fluctuations of CO ₂ in Liquid and Supercritical Phases., The Journal of Physical Chemistry Letters 16;11, 2778-2784 (2025), [doi: 10.1021/acs.jpclett.5c00073, LillOA]
19. M. Guerain, N. T. Correia, L.-V. Roca Paixao, H. Chevreau, F. Affouard, Using synchrotron high-resolution powder X-ray diffraction for the structure determination of a new cocrystal formed by two active principle ingredients, Acta Crystallographica Section C Structural Chemistry 80;2, 37-42 (2024), [doi: 10.1107/s2053229624000639, LillOA]
18. T. Cordeiro, I. Matos, F. Danede, J.C. Sotomayor, I.M. Fonseca, M.C. Corvo, M. Dionísio, M.T. Viciosa, F. Affouard, N. T. Correia, Evidence of Strong Guest–Host Interactions in Simvastatin Loaded in Mesoporous Silica MCM-41, Pharmaceutics 15;5, 1320 (2023), [doi: 10.3390/pharmaceutics15051320, LillOA]
17. L.-V. Roca Paixao, N. T. Correia, F. Danede, M. Guerain, F. Affouard, Carbamazepine/Tartaric Acid Cocrystalline Forms: When Stoichiometry and Synthesis Method Matter, Crystal Growth & Design 23;3, 1355-1369 (2023), [doi: 10.1021/acs.cgd.2c00859, LillOA]
16. L.-V. Roca Paixao, N. T. Correia, F. Danede, M.T. Viciosa, A.L. Morritt, Y.Z. Khimyak, F. Affouard, Nature of the Structural and Dynamical Disorder in Organic Cocrystals with a True Nanometric Size Channel-Like Architecture, Crystal Growth & Design 23;1, 120-133 (2023), [doi: 10.1021/acs.cgd.2c00815, LillOA]
15. P. d’Orey, T. Cordeiro, M.A.O. Lourenço, I. Matos, F. Danede, J.C. Sotomayor, I.M. Fonseca, P. Ferreira, N. T. Correia, M. Dionísio, How Molecular Mobility, Physical State, and Drug Distribution Influence the Naproxen Release Profile from Different Mesoporous Silica Matrices, Molecular Pharmaceutics 18;3, 898-914 (2021), [doi: 10.1021/acs.molpharmaceut.0c00908, LillOA]
14. A.C. Santos, S.P. Alves, G. Carvalhão, N. T. Correia, M.T. Viciosa, J.P.S. Farinha, Phase diagrams of temperature-responsive copolymers p(MEO2MA-co-OEGMA) in water, Polymer 228, 123858 (2021), [doi: 10.1016/j.polymer.2021.123858, LillOA]
13. Y. Vaksler, D. Benedis, A. Dyshin, R. Oparin, N. T. Correia, F. Capet, S. Shishkina, M. Kiselev, A. Idrissi, Spectroscopic characterization of single co-crystal of mefenamic acid and nicotinamide using supercritical CO2, Journal of Molecular Liquids 334, 116117 (2021), [doi: 10.1016/j.molliq.2021.116117, LillOA]
12. B. Malfait, L. Paccou, N. T. Correia, Y. Guinet, A. Hedoux, Identification of an amorphous-amorphous two-step transformation in indomethacin embedded within mesoporous silica, Microporous and Mesoporous Materials 328, 111502 (2021), [doi: 10.1016/j.micromeso.2021.111502, LillOA]
11. B. Atawa, N. Couvrat, F. Affouard, N. T. Correia, G. Coquerel, A. Saiter-Fourcin, Impact of chirality on the amorphous state of conglomerate forming systems: a case study of N-acetyl-α-methylbenzylamine, Physical Chemistry Chemical Physics 23;42, 24282-24293 (2021), [doi: 10.1039/d1cp03843e, LillOA]
10. M. Guerain, Y. Guinet, N. T. Correia, L. Paccou, F. Danede, A. Hedoux, Polymorphism and stability of ibuprofen/nicotinamide cocrystal: The effect of the crystalline synthesis method, International Journal of Pharmaceutics 584, 119454 (2020), [doi: 10.1016/j.ijpharm.2020.119454, LillOA]
9. S. Inocencio, T. Cordeiro, I. Matos, F. Danede, J.C. Sotomayor, I.M. Fonseca, N. T. Correia, M.C. Corvo, M. Dionísio, Ibuprofen incorporated into unmodified and modified mesoporous silica: From matrix synthesis to drug release, Microporous and Mesoporous Materials 310, 110541 (15 p.) (2020), [doi: 10.1016/j.micromeso.2020.110541, LillOA]
8. B. Malfait, N. T. Correia, C. Ciotonea, J. Dhainaut, J.-P. Dacquin, s. royer, N. Tabary, Y. Guinet, A. Hedoux, Manipulating the physical states of confined ibuprofen in SBA-15 based drug delivery systems obtained by solid-state loading: Impact of the loading degree, The Journal of Chemical Physics 153;15, 154506 (2020), [doi: 10.1063/5.0020992, LillOA]
7. M. Guerain, P. Derollez, L.-V. Roca Paixao, C. Dejoie, N. T. Correia, F. Affouard, Structure determination of Carbamazepine/DL-TA co-crystal by synchrotron powder X-ray diffraction, Acta Crystallographica Section C Structural Chemistry 76, (2020), [LillOA]
6. J. Knapik-Kowalczuk, K. Chmiel, K. Jurkiewicz, N. T. Correia, W. Sawicki, M. Paluch, Physical Stability and Viscoelastic Properties of Co-Amorphous Ezetimibe/Simvastatin System, Pharmaceuticals 12;1, 40 (2019), [doi: 10.3390/ph12010040, LillOA]
5. T. Starciuc, B. Malfait, F. Danede, L. Paccou, Y. Guinet, N. T. Correia, A. Hedoux, Trehalose or sucrose; which of the two should be used for stabilizing proteins in the solid state? A dilemma investigated by in-situ micro-Raman and dielectric relaxation spectroscopies during and after freeze-drying, Journal of Pharmaceutical Sciences 109;1, 496-504 (2019), [doi: 10.1016/j.xphs.2019.10.055, LillOA]
4. L.-V. Roca Paixao, N. T. Correia, F. Affouard, Affinity prediction computations and mechanosynthesis of carbamazepine based cocrystals, Crystengcomm 21;45, 6991-7001 (2019), [doi: 10.1039/c9ce01160a, LillOA]
3. A. Benazzouz, E. Dudognon, N. T. Correia, V. Molinier, J.-M. Aubry, M. Descamps, Interactions underpinning the plasticization of a polymer matrix: a dynamic and structural analysis of DMP-plasticized cellulose acetate, Cellulose 24, 487-503 (2017), [doi: 10.1007/s10570-016-1148-y, LillOA]
2. E. Dudognon, N. T. Correia, F. Danede, M. Descamps, Solid-Solid Transformation in Racemic Ibuprofen, Pharmaceutical Research 30, 81-89 (2013), [doi: 10.1007/s11095-012-0851-0, LillOA]
1. A. Hedoux, Y. Guinet, P. Derollez, E. Dudognon, N. T. Correia, Raman spectroscopy of racemic ibuprofen: Evidence of molecular disorder in phase II, International Journal of Pharmaceutics 421, 45-52 (2011), [doi: 10.1016/j.ijpharm.2011.09.015, LillOA]

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Communications

10. L.-V. Roca Paixao, N. T. Correia, F. Danede, M.T. Viciosa, A. Morritt, Y.Z. Khimyak, F. Affouard, Nature of the disorder in organic cocrystals of pharmaceutical interest with a channel-like architecture, Conférence invitée, 9th International Discussion Meeting on Relaxations in Complex Systems (9 IDMRCS), Chiba, Japon, Aou 2023 [LillOA]
9. Y.Z. Khimyak, L. Fabian, A. Morritt, M. Nowak, N. T. Correia, F. Affouard, M. T. Ruggiero, K.P. Nartowski, Understanding phase transitions and nature of disorder in pharmaceutical materials: polymorphs, co-crystals and nano-confined systems, Communication dans un congrès sans actes, Taming Disorder in Solid Materials, Durham, Royaume-Uni, Déc 2023 [LillOA]
8. N. T. Correia, F. Affouard, SYSTÈMES PHARMACEUTIQUES PAR BDS & MD : QUELQUES CAS CURIEUX, Communication dans un congrès sans actes, GDR REEPOS 2023 & SDM 3, Toulouse, France, Juin 2023 [LillOA]
7. T. Cordeiro, M.T. Viciosa, M. Dionísio, F. Affouard, N. T. Correia, Amorphous Simvastatin Confined in MCM-41: Where have the β-JG and α-relaxation processes gone?, Communication dans un congrès sans actes, 9th International Discussion Meeting on Relaxations in Complex Systems (9IDMRCS), Chiba City, Japon, Aou 2023 [LillOA]
6. N. T. Correia, Interests of dielectric relaxation spectroscopy to investigate different properties of pharmaceuticals, Conférence invitée, International Conference on Science and Technology of Pharmaceutical Glass, Tsukuba, Japon, Aou 2023 [LillOA]
5. L.-V. Roca Paixao, F. Danede, N. T. Correia, F. Affouard, WHEN RESIDUAL WATER INFLUENCES THE COCRYSTALLIZATION OUTPUT: THE CARBAMAZEPINE AND TARTARIC ACID CASE, Communication dans un congrès sans actes, Journées SolvATE 2021, Lille, France, Déc 2021 [LillOA]
4. N. T. Correia, T. Cordeiro, F. Affouard, I. Matos, F. Danede, J. Sotomayor, M. Corvo, I. Fonseca, M. Dionísio, M.T. Viciosa, Simvastatine confinée dans MCM-41 : désordre dynamique, organisations/interactions moléculaires et leurs implications sur la vitesse de dissolution et le profil de libération, Poster, Conference Internationale "Matériaux 2022", Lille, France, Oct 2022 [LillOA]
3. N. T. Correia, L.-V. Roca Paixao, F. Affouard, Carbamazepine/Tartaric Acid Ordered and Disordered Cocrystalline Forms: When Stoichiometry and Synthesis Method Matter, Communication dans un congrès sans actes, CGOM14: 14 th International Conference on Crystal Growth of Organic Materials, Bruxelles, Belgique, Sep 2022 [LillOA]
2. N. T. Correia, L.-V. Roca Paixao, F. Danede, M.T. Viciosa, A.L. Morritt, Y.Z. Khimyak, F. Affouard, Dynamic Disorder in a Nano-Sized Channel-Shaped Pharmaceutical Cocrystal Architecture, Conférence invitée, 11th Conference on Broadband Dielectric Spectroscopy and its applications, San Sebastian, Espagne, Sep 2022 [LillOA]
1. L.-V. Roca Paixao, M.T. Viciosa, N. T. Correia, F. Affouard, Dynamical disorder in the solid state: Insights from dielectric relaxation spectroscopies, Poster, 32nd European Crystallographic Meeting (ECM32), Vienna, Autriche, Aou 2019 [LillOA]

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