Frédéric AFFOUARD

Professor

Bâtiment P5 - 221
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0)3 20 43 68 15
Fax: +33 (0)3 20 43 40 84
Email : Send an email to Frédéric AFFOUARD
ORCID Identifier : 0000-0001-8429-6416

Research team: Matériaux moléculaires et thérapeutiques

Research

Physical states of molecular materials. Physical mechanisms of the glass transition of molecular materials composed of small organic molecules (glassy crystals, liquids). Optimization of the stability of biomolecules. Molecular dynamics simulation. Neutron scattering.

Teaching

Faculty of Sciences - Department of Physics : -  2nd and 3rd year: "Students Projects: Innovative Materials and Green chemistry" - Master1 (Physics of the XXIst century ): "Thermodynamics & Statistical Physics" - Master2: (Materials, Molecules and their Environnements) "Phase transformation", "Molecular modelling". Coordinator of the Erasmus Mundus BIOPHAM Master  "bio&Pharmaceutical Materials Science" https://www.master-biopham.eu

Current PhD thesis

• Fabien PUGA MONTESDEOCA, Étude numérique et expérimentale des interactions intermoléculaires et du désordre dynamique dans les cocristaux d'intérêt pharmaceutique . Thesis started in 2023. Other co-advisor: Natalia T. CORREIA.

Defended PhD thesis

• Simon SAMSOEN, Design et caractérisation physique de matrices polymères pour l’optimisation de la libération de principes actifs pharmaceutiques . Thesis defended in 2024. Other co-advisors: Patrice WOISEL, Emeline DUDOGNON.
• Jeanne-Annick BAMA, Stabilité et mobilité des matériaux pharmaceutiques multi composants moléculaires . Thesis defended in 2021. Other co-advisor: Emeline DUDOGNON. Position: Clinical trial associate at AQUILAB.
• Luisa ROCA PAIXAO, Investigation de l'état physique de nouveaux matériaux pour la formulation de molécules pharmaceutiques de très faible solubilité . Thesis defended in 2020. Other co-advisor: Natalia T. CORREIA. Position: Solid state scientist at the Janssen Pharmaceutical compagnies of Johnson & Johnson.
• Frédéric NGONO MEBENGA, Study of amorphous pharmaceutical materials by molecular dynamics simulation and neutron scattering. Thesis defended in 2017. Other co-advisor: Jean-François WILLART. Position: Principal scientist at JANSSEN Pharmaceutica N.V.
• Joseph Gerges, Numerical study of the physical factors responsible for the ability to vitrify / recrystallization model material of pharmaceutical interest. Thesis defended in 2015. Position: Enseignant-Formateur.
• Martin Thierry Ottou Abe, Study by simulation of molecular dynamics of the structure and molecular mobility of complex materials of therapeutic interest
  THESIS COSUPERVISED WITH PROF. NDJAKA (UNIVERSITY YAOUNDE 1 CAMEROUN). Thesis defended in 2014. Position: Chargé de Recherche (Univ. Yaoundé I, Cameroun).
• Samira Achir, The protein stabilizing mechanisms investigated by Raman scattering and molecular dynamics simulations. Thesis defended in 2014. Other co-advisor: Alain HEDOUX. Position: Enseignante/Formatrice chez Université européenne des métiers de la finition CFA Gestes Formation.
• Rémy Dubois, Numerical and experimental investigation of the stability and solubility of amorphous pharmaceutical solids to improve the bioavailability of drugs. Thesis defended in 2013.
• Rémi Busselez, Study of bioprotectant fluids under confinement. Thesis defended in 2008. Other co-advisor: Denis Morineau.
• Adrien Lerbret, Study of the biopreservative capabilities of sugars: investigation from molecular dynamics and Raman spectroscopy. Thesis defended in 2005. Other co-advisors: Alain HEDOUX, Marc DESCAMPS. Position: Ingénieur de Recherche - Université de Bourgogne-AgroSup Dijon.