Florence DANEDE

Ingénieur en techniques des sciences des matériaux/caractérisation Université de Lille

Bâtiment P5 - 227
Unité Matériaux et Transformations
Cité scientifique, Bât. P5
Université de Lille
59655 Villeneuve d'Ascq
France
Tel: +33 (0)3 20 43 47 08
Fax: +33 (0)3 20 43 40 84
Courriel : Envoyer un mel à Florence DANEDE
Identifiant ORCID : 0000-0001-5139-9187

Equipe: Matériaux moléculaires et thérapeutiques

Activité

Diffraction des rayons X sur poudre Analyses thermiques (DSC, DSC modulée, ATG) Préparation des échantillons Personne Compétente en Radioprotection

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ATG Q500 (TA Instruments)

Equipe : Matériaux moléculaires et thérapeutiques.

Correspondant : Florence DANEDE.

Caractérisation des pertes de solvants et dégradations dans les matériaux moléculaires
Gamme de température : de 30°C à 550°C

 

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Diffractomètre à Rayons X sur poudres, X'Pert Pro (Panalytical)

Equipe : Matériaux moléculaires et thérapeutiques.

Plateforme : Plateau d’analyses par diffraction des Rayons X.

Correspondants : Mathieu GUERAIN, Florence DANEDE.

Etude de l'organisation structurale de matériaux moléculaires : états  vitreux et transformations de phases induites par des contraintes externes (variations de température, broyage, vieillissement, ...)
Caractéristiques techniques

• Tube au cuivre
• Mesures en transmission sur échantillons conditionnés en capillaires avec la possibilité de varier la température de l'ambiante à 300°C ( four Huber)
• Mesures en réflexion sur plaquettes avec la possibilité de varier la température de -150°C à 400°C (chambre Anton Paar TTK 450)

 

Responsabilité d'instruments

Derniers dépôts dans dans LillOA (Lille Open Archive)

Publications

21. A. Barrera, C. Binet, F. Danede, J.-F. Tahon, B. OUDDANE, F. Dubois, P. Supiot, C. Foissac, U. Maschke, Chemical Characterization and Thermal Analysis of Recovered Liquid Crystals, Crystals 13;7, 1064 (2023), [doi: 10.3390/cryst13071064, LillOA]
20. A. Krupa, F. Danede, D. Majda, A. Węgrzyn, D. Strojewski, I. Kondera, J.-F. willart, High energy ball milling vs. nano spray drying in the development of supersaturated systems loaded with bosentan, European Journal of Pharmaceutics and Biopharmaceutics 188, 137-146 (2023), [doi: 10.1016/j.ejpb.2023.05.014, LillOA]
19. S. Wachowiak, F. Danede, J.-F. willart, F. Siepmann, J. Siepmann, M. Hamoudi, PLGA implants for controlled dexamethasone delivery: Impact of the polymer chemistry, Journal of Drug Delivery Science and Technology 86, 104648 (2023), [doi: 10.1016/j.jddst.2023.104648, LillOA]
18. C. Henaff, J. Siepmann, F. Siepmann, F. Danede, M.-N. Avettand-Fènoël, J. VERIN, A. Fadel, J.-F. willart, Exploration of the physical states of riboflavin (free base) by mechanical milling, International journal of pharmaceutics 645, 123416 (2023), [doi: 10.1016/j.ijpharm.2023.123416, LillOA]
17. T. Rongthong, A. Qnouch, M. Maue Gehrke, L. Paccou, P. Oliveira, F. Danede, J. VERIN, C. Vincent, J.-F. willart, F. Siepmann, J. Siepmann, Silicone matrices for controlled dexamethasone release: toward a better understanding of the underlying mass transport mechanisms., Regenerative Biomaterials 10, rbad008 (2023), [doi: 10.1093/rb/rbad008, LillOA]
16. L.-V. Roca Paixao, N. T. Correia, F. Danede, M.T. Viciosa, A.L. Morritt, Y.Z. Khimyak, F. Affouard, Nature of the Structural and Dynamical Disorder in Organic Cocrystals with a True Nanometric Size Channel-Like Architecture, Crystal Growth & Design 23;1, 120-133 (2023), [doi: 10.1021/acs.cgd.2c00815, LillOA]
15. T. Rongthong, A. Qnouch, M.M. Gehrke, F. Danede, J.-F. willart, P.F.M. De Oliveira, L. Paccou, G. Tourrel, P. Stahl, J. VERIN, P. Toulemonde, C. Vincent, F. Siepmann, J. Siepmann, Long term behavior of dexamethasone-loaded cochlear implants: In vitro & in vivo, International Journal of Pharmaceutics: X 4, 100141 (2022), [doi: 10.1016/j.ijpx.2022.100141, LillOA]
14. Y. Guinet, L. Paccou, F. Danede, P. Derollez, A. Hedoux, Identification of incommensurability in L-leucine: can lattice instabilities be considered as general phenomena in hydrophobic amino acids?, Physical Chemistry Chemical Physics 24, 27023-27030 (2022), [doi: 10.1039/d2cp00989g, LillOA]
13. C. Bassand, L. Benabed, J. Verin, F. Danede, L. Lefol, J.-F. willart, F. Siepmann, J. Siepmann, Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state, JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 73, 103432 (2022), [doi: 10.1016/j.jddst.2022.103432, LillOA]
12. C. Bassand, L. Benabed, J. Verin, F. Danede, L. Lefol, J.-F. willart, F. Siepmann, J. Siepmann, Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state, JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 73, 103432 (2022), [doi: 10.1016/j.jddst.2022.103432, LillOA]
11. C. Bassand, L. Benabed, J. Verin, F. Danede, L. Lefol, J.-F. willart, F. Siepmann, J. Siepmann, L. Benabed, Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state, Journal of Drug Delivery Science and Technology 73, 103432 (2022), [doi: 10.1016/j.jddst.2022.103432, LillOA]
10. J.-F. willart, S. Ouerghemmi, N. Descamps, P. Heijboer, L. Paccou, F. Danede, M. Descamps, The melting of glucose, International Journal of Pharmaceutics 626, 122185 (2022), [doi: 10.1016/j.ijpharm.2022.122185, LillOA]
9. A. Krupa, F. Danede, A. Węgrzyn, D. Majda, J.-F. willart, Thinking of bosentan repurposing – A study on dehydration and amorphization, International Journal of Pharmaceutics 622, 121846 (2022), [doi: 10.1016/j.ijpharm.2022.121846, LillOA]
8. A. Dupont, M. Guerain, F. Danede, J.-F. willart, Evidence of transient amorphization during the polymorphic transformation of sorbitol induced by milling, International Journal of Pharmaceutics 121929 (2022), [doi: 10.1016/j.ijpharm.2022.121929, LillOA]
7. Y. Guinet, L. Paccou, F. Danede, A. Hedoux, Revisiting the phase transition sequence in L-methionine: Description of the disordering mechanism in an essential amino acid, Journal of Chemical Physics 156;3, 034501 (2022), [doi: 10.1063/5.0077743, LillOA]
6. E. Dudognon, F. Danede, M. Guerain, Milling-induced Phase Transformations, Underlying Mechanisms and Resulting Physical States in an Enantiotropic System: the Case of Bezafibrate, Crystal Growth & Design 22;1, 363-378 (2022), [doi: 10.1021/acs.cgd.1c00997, LillOA]
5. Y. Benzine, F. Siepmann, C. Neut, F. Danede, J.-F. willart, J. Siepmann, y. karrout, Injection-molded capsule bodies and caps based on polymer blends for controlled drug delivery, European Journal of Pharmaceutics and Biopharmaceutics 168, 1-14 (2021), [doi: 10.1016/j.ejpb.2021.08.007, LillOA]
4. Y. Guinet, L. Paccou, F. Danede, A. Hedoux, Confinement of molecular materials using a solid-state loading method: a route for exploring new physical states and their subsequent transformation highlighted by caffeine confined to SBA-15 pores, RSC Advances 11;55, 34564-34571 (2021), [doi: 10.1039/D1RA05757J, LillOA]
3. M. Guerain, F. Affouard, C. Henaff, C. Dejoie, F. Danede, J. Siepmann, F. Siepmann, J.-F. willart, Structure determination of riboflavin by synchrotron high-resolution powder X-ray diffraction, Acta Crystallographica Section C Structural Chemistry 77;12, 800-806 (2021), [doi: 10.1107/s2053229621012171, LillOA]
2. A. Qnouch, V. Solarczyk, J. Verin, G. Tourrel, P. Stahl, F. Danede, J.-F. willart, P.-E. Lemesre, C. Vincent, J. Siepmann, F. Siepmann, Dexamethasone-loaded cochlear implants: How to provide a desired “burst release”, International Journal of Pharmaceutics: X 100088 (2021), [doi: 10.1016/j.ijpx.2021.100088, LillOA]
1. M. Guerain, Y. Guinet, N. T. Correia, L. Paccou, F. Danede, A. Hedoux, Polymorphism and stability of ibuprofen/nicotinamide cocrystal: The effect of the crystalline synthesis method, International Journal of Pharmaceutics 584, 119454 (2020), [doi: 10.1016/j.ijpharm.2020.119454, LillOA]

Liste complète (Le lien peut être lent)

Communications

10. L.-V. Roca Paixao, F. Danede, N. T. Correia, F. Affouard, WHEN RESIDUAL WATER INFLUENCES THE COCRYSTALLIZATION OUTPUT: THE CARBAMAZEPINE AND TARTARIC ACID CASE, Communication dans un congrès sans actes, Journées SolvATE 2021, Lille, France, Déc 2021 [LillOA]
9. N. T. Correia, T. Cordeiro, F. Affouard, I. Matos, F. Danede, J. Sotomayor, M. Corvo, I. Fonseca, M. Dionísio, M.T. Viciosa, Simvastatine confinée dans MCM-41 : désordre dynamique, organisations/interactions moléculaires et leurs implications sur la vitesse de dissolution et le profil de libération, Poster, Conference Internationale "Matériaux 2022", Lille, France, Oct 2022 [LillOA]
8. N. T. Correia, L.-V. Roca Paixao, F. Danede, M.T. Viciosa, A.L. Morritt, Y.Z. Khimyak, F. Affouard, Dynamic Disorder in a Nano-Sized Channel-Shaped Pharmaceutical Cocrystal Architecture, Conférence invitée, 11th Conference on Broadband Dielectric Spectroscopy and its applications, San Sebastian, Espagne, Sep 2022 [LillOA]
7. L.-V. Roca Paixao, F. Danede, M. Guerain, N. T. Correia, F. Affouard, Affinity Prediction And Synthesis Of Carbamazepine-based Cocrystals, Poster, 17th European Conference on Solid State Chemistry (ECSSC17), Villeneuve d'Ascq, France, Sep 2019 [LillOA]
6. M. Guerain, P. Derollez, C. Dejoie, N. T. Correia, F. Danede, F. Affouard, L. Paccou, Y. Guinet, A. Hedoux, C. Dejoie, Analyse structurale de matériaux moléculaires thérapeutiques cocristallisés par diffraction des rayons X, Communication dans un congrès sans actes, Rayons X et Matière 2019, Nancy, France, Nov 2019 [LillOA]
5. F. Tamani, C. Bassand, M.H.-B. Yelles, J.-F. willart, F. Danede, F. Siepmann, J. Siepmann, How single PLGA microparticles behave, Poster, 3rd European Conference on Pharmaceutics, Bologne, Italie, Mar 2018 [LillOA]
4. T. Rongthong, M. Gehrke, P. Oliveira, F. Danede, J.-F. willart, C. Vincent, F. Siepmann, J. Siepmann, Silicone matrices for controlled drug delivery to the inner ear: Effects of the drug form and agglomerates, Poster, 11th world meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical technology, Granada, Espagne, Mar 2018 [LillOA]
3. A. Krupa, M. Descamps, J.-F. willart, F. Danede, E. Wyska, R. Jachowicz, The technological solutions to enhance the bioavailability of tadalafil, Communication dans un congrès sans actes, The 1st International Conference on Contemporary Pharmacy Challenges, Wisla, Pologne, Sep 2018 [LillOA]
2. M. Dionísio, T. Cordeiro, S. Inocêncio, M.C. Corvo, I. Matos, J. Sotomayor, I. Fonseca, M.M. Cardoso, M.T. Viciosa, F. Danede, F. Affouard, N. T. Correia, Stabilizing high internal energetic states of pharmaceutical drugs by nanoconfinement, Communication dans un congrès sans actes, 0th Conference on BROADBAND DIELECTRIC SPECTROSCOPY AND ITS APPLICATIONS, Brussels, Belgique, Aou 2018 [LillOA]
1. L.-V. Roca Paixao, F. Danede, M. Guerain, N. T. Correia, F. Affouard, Coformers predictions, synthesis and characterization of pharmaceutical cocrystals, Communication dans un congrès sans actes, 13th International Workshop of the Crystal Growth of Organic Material (CGOM13), Seoul, Corée du Sud, Aou 2018 [LillOA]

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